Second-generation growth hormone releasing peptide and ghrelin receptor agonist.
GHRP-2 is a research compound available through our china peptide catalog as a finished, lyophilized vial from an established Chinese manufacturer. It belongs to the Synthetic hexapeptide (second-generation GH secretagogue)
Research Areas
GH axis pharmacology, pituitary function, GHS-R1a structure-activity, GH deficiency models
Available Variants
| Name | Strength | Pack Size | Purity | Availability |
|---|---|---|---|---|
| GHRP-2 | 5 mg | 10 vials | ≥98% | In Stock |
| GHRP-2 | 10 mg | 10 vials | ≥98% | In Stock |
| GHRP-2 | 15 mg | 10 vials | ≥98% | In Stock |
Specification Highlights
Quality & Testing
Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .
**Where provided, these documents reflect the manufacturer’s batch testing for this compound.
Research Areas
Pituitary GH Secretion Research GHRP-2 reliably stimulates GH release from anterior pituitary somatotrophs in rodent and primate models, making it a standard pituitary function probe. Research has characterized GH pulse profiles following GHRP-2 administration, including peak concentration, pulse duration, and dose-response relationships. It is frequently used in GH deficiency models to assess secretagogue responsiveness as a functional diagnostic tool. GHS-R1a Structure-Activity Research The 2-naphthylalanine substitution in GHRP-2 (replacing tryptophan in GHRP-6) has been of significant interest in GHS-R1a structure-activity relationship studies. Research has compared binding affinities, receptor internalization rates, and downstream signaling profiles between GHRP-2, GHRP-6, and natural ghrelin to map receptor pharmacophore requirements — contributing to rational design of improved GHS-R1a ligands. GHRH Synergy and Combination Protocols GHRP-2 combined with GHRH analogues (CJC-1295, sermorelin) has been extensively studied in GH secretagogue research. The combination engages both GHS-R1a and GHRHR simultaneously, producing synergistic amplification of GH pulses beyond what either agent achieves alone. This synergy has been a primary research design tool for studying GH axis reserve and pituitary responsiveness. ## Sourcing GHRP-2 From China
GHRP-2 is available through our platform as a china peptide sourced directly from an established Chinese manufacturer. Three points define how we handle it:
- Factory-direct, not trader-sourced. We confirm availability and specification with the manufacturer before the order is confirmed. There is no intermediary resale of unknown-origin vials in this catalog.
- Specification before shipment. The purity and concentration specification shown on this page is the manufacturer’s batch specification. Product-specific quality-control information travels with the order.
- Research-use discipline. Like every listing in our catalog, GHRP-2 is supplied for laboratory research use only, under strict research-use terms.
For buyers comparing chinese peptides suppliers, the practical test is whether the seller can name the manufacturer and show the batch documentation. We work the other way around: the manufacturer and the documentation are the offer. Browse the full catalog or see how sourcing works.
Available Variants
| Name | Strength | Pack Size | Purity | Availability |
|---|---|---|---|---|
| GHRP-2 | 5 mg | 10 vials | ≥98% | In Stock |
| GHRP-2 | 10 mg | 10 vials | ≥98% | In Stock |
| GHRP-2 | 15 mg | 10 vials | ≥98% | In Stock |
Specification Highlights
Quality & Testing
Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .
**Where provided, these documents reflect the manufacturer’s batch testing for this compound.
Research Areas
Pituitary GH Secretion Research GHRP-2 reliably stimulates GH release from anterior pituitary somatotrophs in rodent and primate models, making it a standard pituitary function probe. Research has characterized GH pulse profiles following GHRP-2 administration, including peak concentration, pulse duration, and dose-response relationships. It is frequently used in GH deficiency models to assess secretagogue responsiveness as a functional diagnostic tool. GHS-R1a Structure-Activity Research The 2-naphthylalanine substitution in GHRP-2 (replacing tryptophan in GHRP-6) has been of significant interest in GHS-R1a structure-activity relationship studies. Research has compared binding affinities, receptor internalization rates, and downstream signaling profiles between GHRP-2, GHRP-6, and natural ghrelin to map receptor pharmacophore requirements — contributing to rational design of improved GHS-R1a ligands. GHRH Synergy and Combination Protocols GHRP-2 combined with GHRH analogues (CJC-1295, sermorelin) has been extensively studied in GH secretagogue research. The combination engages both GHS-R1a and GHRHR simultaneously, producing synergistic amplification of GH pulses beyond what either agent achieves alone. This synergy has been a primary research design tool for studying GH axis reserve and pituitary responsiveness.
Compound Profile
GHRP-2 (Growth Hormone Releasing Peptide-2) is a second-generation synthetic hexapeptide and GHS-R1a agonist, developed as an improvement over first-generation secretagogues including GHRP-6. Its sequence — D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂ — incorporates a 2-naphthylalanine residue at position 2 in place of the tryptophan found in GHRP-6, a modification associated with increased receptor binding potency and reduced prolactin-stimulating effects. GHRP-2 is widely used in preclinical research as a reference GH secretagogue with a cleaner pharmacological profile compared to earlier compounds. In rodent models, GHRP-2 produces robust GH pulse stimulation via GHS-R1a agonism, with documented lower ghrelin receptor efficacy than GHRP-6 — resulting in reduced appetite stimulation while maintaining or enhancing GH secretory amplitude. Research interest includes its use as a pituitary function probe, as a synergistic partner with GHRH analogues, and as a comparison compound for evaluating newer GHS-R1a ligands in structural studies. Its predictable pharmacokinetics and validated effects in multiple species make it a standard research tool. Peptides of China supplies GHRP-2 as a lyophilized powder at 99%+ purity, verified by HPLC and Mass Spectrometry. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control. All products are for laboratory research use only and are not for human consumption.
Profile
Research Areas
GH axis pharmacology, pituitary function, GHS-R1a structure-activity, GH deficiency models
Available Variants
| Name | Strength | Pack Size | Purity | Availability |
|---|---|---|---|---|
| GHRP-2 | 5 mg | 10 vials | ≥98% | In Stock |
| GHRP-2 | 10 mg | 10 vials | ≥98% | In Stock |
| GHRP-2 | 15 mg | 10 vials | ≥98% | In Stock |
Specification Highlights
Quality & Testing
Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .
**Where provided, these documents reflect the manufacturer’s batch testing for this compound.
Research Areas
Pituitary GH Secretion Research GHRP-2 reliably stimulates GH release from anterior pituitary somatotrophs in rodent and primate models, making it a standard pituitary function probe. Research has characterized GH pulse profiles following GHRP-2 administration, including peak concentration, pulse duration, and dose-response relationships. It is frequently used in GH deficiency models to assess secretagogue responsiveness as a functional diagnostic tool. GHS-R1a Structure-Activity Research The 2-naphthylalanine substitution in GHRP-2 (replacing tryptophan in GHRP-6) has been of significant interest in GHS-R1a structure-activity relationship studies. Research has compared binding affinities, receptor internalization rates, and downstream signaling profiles between GHRP-2, GHRP-6, and natural ghrelin to map receptor pharmacophore requirements — contributing to rational design of improved GHS-R1a ligands. GHRH Synergy and Combination Protocols GHRP-2 combined with GHRH analogues (CJC-1295, sermorelin) has been extensively studied in GH secretagogue research. The combination engages both GHS-R1a and GHRHR simultaneously, producing synergistic amplification of GH pulses beyond what either agent achieves alone. This synergy has been a primary research design tool for studying GH axis reserve and pituitary responsiveness.