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Cagrilintide

Cagrilintide — research peptide from China

Compound Profile

Chemical Class
Acylated amylin analogue
Synonyms
IcoSema amylin component, AM833
Sequence
Available on request (37-aa amylin analogue, C18 fatty-diacid acylation)
Amino Acids
26 (modified human amylin sequence)
Receptor Target
AMY1, AMY2, AMY3 (amylin receptor subtypes)
Molecular Formula
N/A — acylated analogue of amylin
Molecular Weight
~3367 Da (with C20 fatty acid modification)
CAS Number
2173468-47-0
Form
Lyophilized powder
Storage
−20°C long-term; 2-8°C aqueous (short-term, use promptly)
Category
Weight Management
Total variants
4
In-stock variants
4 of 4
Purity
≥98%
Standard pack size
10 vials

Cagrilintide research peptide sourced from verified Chinese synthesis facility. Long-acting amylin analog. Purity tested per batch, wholesale B2B pricing.

Cagrilintide is a research compound available through our china peptide catalog as a finished, lyophilized vial from an established Chinese manufacturer. It belongs to the Acylated amylin analogue

Research Areas

Metabolic regulation, appetite signaling, gastric emptying, amylin receptor pharmacology

Available Variants

Name Strength Pack Size Purity Availability
Cagrilintide 5 mg 10 vials ≥98% In Stock
Cagrilintide 5 mg 10 vials — In Stock
Cagrilintide 10 mg 10 vials ≥98% In Stock
Cagrilintide 10 mg 10 vials — In Stock

Specification Highlights

Quality & Testing

Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Endotoxins”,“Microbiology”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .

**Where provided, these documents reflect the manufacturer’s batch testing for this compound.

Research Areas

Amylin Receptor Pharmacology Cagrilintide binds amylin receptor complexes (AMY1-3), which are heterodimers of the calcitonin receptor and receptor activity-modifying proteins (RAMPs). Research has focused on how fatty acid acylation affects receptor binding affinity, selectivity between AMY subtypes, and duration of action compared to native human amylin and earlier analogues. The long half-life achieved through acylation is a primary pharmacokinetic research interest. Energy Intake and Satiety Signaling Studies have examined cagrilintide’s effects on food intake in diet-induced obesity rodent models. Proposed mechanisms include signaling through hindbrain amylin receptors in the area postrema and nucleus tractus solitarius, regions involved in satiety processing. Complementary action with GLP-1 receptor agonists at distinct central sites has been a key hypothesis driving combination research. Metabolic Parameter Research Research has examined cagrilintide’s influence on gastric emptying, glucagon secretion, and body weight outcomes in preclinical models. Its metabolic profile — distinct from GLP-1, GIP, or glucagon receptor pathways — positions it as a tool compound for studying amylinergic contributions to energy homeostasis independent of incretin signaling. ## Sourcing Cagrilintide From China

Cagrilintide is available through our platform as a china peptide sourced directly from an established Chinese manufacturer. Three points define how we handle it:

  • Factory-direct, not trader-sourced. We confirm availability and specification with the manufacturer before the order is confirmed. There is no intermediary resale of unknown-origin vials in this catalog.
  • Specification before shipment. The purity and concentration specification shown on this page is the manufacturer’s batch specification. Product-specific quality-control information travels with the order.
  • Research-use discipline. Like every listing in our catalog, Cagrilintide is supplied for laboratory research use only, under strict research-use terms.

For buyers comparing chinese peptides suppliers, the practical test is whether the seller can name the manufacturer and show the batch documentation. We work the other way around: the manufacturer and the documentation are the offer. Browse the full catalog or see how sourcing works.

Available Variants

Name Strength Pack Size Purity Availability
Cagrilintide 5 mg 10 vials ≥98% In Stock
Cagrilintide 5 mg 10 vials — In Stock
Cagrilintide 10 mg 10 vials ≥98% In Stock
Cagrilintide 10 mg 10 vials — In Stock

Specification Highlights

Quality & Testing

Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Endotoxins”,“Microbiology”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .

**Where provided, these documents reflect the manufacturer’s batch testing for this compound.

Research Areas

Amylin Receptor Pharmacology Cagrilintide binds amylin receptor complexes (AMY1-3), which are heterodimers of the calcitonin receptor and receptor activity-modifying proteins (RAMPs). Research has focused on how fatty acid acylation affects receptor binding affinity, selectivity between AMY subtypes, and duration of action compared to native human amylin and earlier analogues. The long half-life achieved through acylation is a primary pharmacokinetic research interest. Energy Intake and Satiety Signaling Studies have examined cagrilintide’s effects on food intake in diet-induced obesity rodent models. Proposed mechanisms include signaling through hindbrain amylin receptors in the area postrema and nucleus tractus solitarius, regions involved in satiety processing. Complementary action with GLP-1 receptor agonists at distinct central sites has been a key hypothesis driving combination research. Metabolic Parameter Research Research has examined cagrilintide’s influence on gastric emptying, glucagon secretion, and body weight outcomes in preclinical models. Its metabolic profile — distinct from GLP-1, GIP, or glucagon receptor pathways — positions it as a tool compound for studying amylinergic contributions to energy homeostasis independent of incretin signaling.

Compound Profile

Cagrilintide is a long-acting acylated amylin analogue developed for metabolic research. Structurally derived from human amylin (IAPP — islet amyloid polypeptide), it is modified with a C20 fatty diacid chain to extend its plasma half-life to approximately 7 days, enabling once-weekly administration in clinical protocols. Research interest centers on its action at amylin receptors (AMY1, AMY2, AMY3) in the hypothalamus and area postrema, which are distinct from the GLP-1 receptor pathway targeted by semaglutide and related compounds. Preclinical and early clinical studies have examined cagrilintide’s role in energy intake regulation, gastric emptying rate, and glucagon suppression. Unlike GLP-1 receptor agonists, amylin analogues appear to act via complementary central pathways, with satiety signals mediated through hindbrain amylin receptor populations. This mechanistic distinction has generated research interest in dual-agonism approaches combining amylin and GLP-1 receptor activity — most notably in the CagriSema combination, currently in phase 3 clinical evaluation. Peptides of China supplies cagrilintide as a lyophilized powder in sealed vials at 99%+ purity, verified by HPLC and Mass Spectrometry. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control. All products are supplied for laboratory research use only and are not for human consumption.

Profile

Research Areas

Metabolic regulation, appetite signaling, gastric emptying, amylin receptor pharmacology

Available Variants

Name Strength Pack Size Purity Availability
Cagrilintide 5 mg 10 vials ≥98% In Stock
Cagrilintide 5 mg 10 vials — In Stock
Cagrilintide 10 mg 10 vials ≥98% In Stock
Cagrilintide 10 mg 10 vials — In Stock

Specification Highlights

Quality & Testing

Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Endotoxins”,“Microbiology”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .

**Where provided, these documents reflect the manufacturer’s batch testing for this compound.

Research Areas

Amylin Receptor Pharmacology Cagrilintide binds amylin receptor complexes (AMY1-3), which are heterodimers of the calcitonin receptor and receptor activity-modifying proteins (RAMPs). Research has focused on how fatty acid acylation affects receptor binding affinity, selectivity between AMY subtypes, and duration of action compared to native human amylin and earlier analogues. The long half-life achieved through acylation is a primary pharmacokinetic research interest. Energy Intake and Satiety Signaling Studies have examined cagrilintide’s effects on food intake in diet-induced obesity rodent models. Proposed mechanisms include signaling through hindbrain amylin receptors in the area postrema and nucleus tractus solitarius, regions involved in satiety processing. Complementary action with GLP-1 receptor agonists at distinct central sites has been a key hypothesis driving combination research. Metabolic Parameter Research Research has examined cagrilintide’s influence on gastric emptying, glucagon secretion, and body weight outcomes in preclinical models. Its metabolic profile — distinct from GLP-1, GIP, or glucagon receptor pathways — positions it as a tool compound for studying amylinergic contributions to energy homeostasis independent of incretin signaling.

Frequently Asked Questions

What is CagriSema and how does it relate to cagrilintide?

CagriSema is the clinical name for the co-administration of cagrilintide and semaglutide in a fixed-ratio combination. It combines amylin receptor agonism (cagrilintide) and GLP-1 receptor agonism (semaglutide) in a single research protocol. Both components are available separately through Peptides of China.

What purity level is your cagrilintide?

Cagrilintide is synthesized to 99%+ purity, verified by HPLC and Mass Spectrometry. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control.

What are the storage requirements for cagrilintide?

Lyophilized cagrilintide should be stored at −20°C, protected from light and moisture. Reconstituted solutions should be kept at 2-8°C and used promptly due to the acylated modification.

Research use only. This product is a research compound intended for laboratory research purposes. It is not for human or veterinary use, and is not a medicine, dietary supplement, or cosmetic.

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