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relaxation-pm

relaxation-pm — research peptide from China

Compound Profile

Chemical Class
Neurotransmitter and neuromodulator injectable combination
Sequence
N/A — complex mixture
Molecular Formula
N/A — complex mixture
Molecular Weight
N/A — complex mixture
CAS Number
N/A — complex mixture
Form
Sterile liquid formulation
Storage
2-8°C; protect from light; do not freeze
Volume
10 ml vial
Research Axes
GABAergic inhibitory signaling, circadian rhythm / MT1/MT2, nNOS/NO pathway, glutamine-GABA precursor cycle
Category
Cognitive & Neuro, Blends
Total variants
1
In-stock variants
1 of 1
Purity
>=98%
Standard pack size
10 vials

Compounded sleep-support injectable containing GABA 100mg, Melatonin 1mg, L-Arginine 100mg, and L-Glutamine 25mg per ml.

relaxation-pm is a research compound available through our china peptide catalog as a finished, lyophilized vial from an established Chinese manufacturer. It belongs to the Neurotransmitter and neuromodulator injectable combination

Research Areas

GABAergic neuropharmacology, circadian biology, neuronal NO signaling, sleep/wake cycle research, ammonia metabolism

Available Variants

Name Strength Pack Size Purity Availability
Relaxation PM 10 ml 10 vials >=98% In Stock

Specification Highlights

Quality & Testing

Testing method: HPLC / LC-MS . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control, using methods such as HPLC and LC-MS. These results are kept in the manufacturer’s internal quality-control records and are not issued as a separate certificate or document.

Research Areas

GABAergic Pathway Research GABA-A and GABA-B receptor pharmacology is studied in neuronal cell cultures (primary cortical neurons, GABAergic interneuron preparations) and brain slice preparations. GABA-A receptor modulation (chloride conductance, inhibitory postsynaptic potential frequency and amplitude) and GABA-B receptor signaling (Gi/o-coupled K⁺ channel activation, Ca²⁺ channel inhibition) are measured electrophysiologically. The Glutamine-Glutamate-GABA cycle — where Glutamine is converted by glutaminase to Glutamate and then by GAD (glutamic acid decarboxylase) to GABA — is an additional research axis provided by the L-Glutamine component. Circadian Rhythm and Melatonin Signaling Melatonin acts on MT1 receptors to suppress SCN (suprachiasmatic nucleus) firing and on MT2 receptors to phase-shift the circadian clock. Research using melatonin examines receptor binding kinetics (radioligand displacement with 2-[¹²⁵I]-iodomelatonin), circadian phase resetting (Per1/Per2 gene expression in circadian reporter cell lines), and antioxidant activity (ORAC, DPPH assays). Combined with GABA (which also modulates SCN activity via GABA-A receptors), the formulation provides dual inhibitory tone for sleep-related neurophysiology research. ## Sourcing relaxation-pm From China

relaxation-pm is available through our platform as a china peptide sourced directly from an established Chinese manufacturer. Three points define how we handle it:

  • Factory-direct, not trader-sourced. We confirm availability and specification with the manufacturer before the order is confirmed. There is no intermediary resale of unknown-origin vials in this catalog.
  • Specification before shipment. The purity and concentration specification shown on this page is the manufacturer’s batch specification. Product-specific quality-control information travels with the order.
  • Research-use discipline. Like every listing in our catalog, relaxation-pm is supplied for laboratory research use only, under strict research-use terms.

For buyers comparing chinese peptides suppliers, the practical test is whether the seller can name the manufacturer and show the batch documentation. We work the other way around: the manufacturer and the documentation are the offer. Browse the full catalog or see how sourcing works.

Available Variants

Name Strength Pack Size Purity Availability
Relaxation PM 10 ml 10 vials >=98% In Stock

Specification Highlights

Quality & Testing

Testing method: HPLC / LC-MS . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control, using methods such as HPLC and LC-MS. These results are kept in the manufacturer’s internal quality-control records and are not issued as a separate certificate or document.

Research Areas

GABAergic Pathway Research GABA-A and GABA-B receptor pharmacology is studied in neuronal cell cultures (primary cortical neurons, GABAergic interneuron preparations) and brain slice preparations. GABA-A receptor modulation (chloride conductance, inhibitory postsynaptic potential frequency and amplitude) and GABA-B receptor signaling (Gi/o-coupled K⁺ channel activation, Ca²⁺ channel inhibition) are measured electrophysiologically. The Glutamine-Glutamate-GABA cycle — where Glutamine is converted by glutaminase to Glutamate and then by GAD (glutamic acid decarboxylase) to GABA — is an additional research axis provided by the L-Glutamine component. Circadian Rhythm and Melatonin Signaling Melatonin acts on MT1 receptors to suppress SCN (suprachiasmatic nucleus) firing and on MT2 receptors to phase-shift the circadian clock. Research using melatonin examines receptor binding kinetics (radioligand displacement with 2-[¹²⁵I]-iodomelatonin), circadian phase resetting (Per1/Per2 gene expression in circadian reporter cell lines), and antioxidant activity (ORAC, DPPH assays). Combined with GABA (which also modulates SCN activity via GABA-A receptors), the formulation provides dual inhibitory tone for sleep-related neurophysiology research.

Compound Profile

Relaxation PM is a compounded injectable formulation containing GABA 100 mg, Melatonin 1 mg, L-Arginine 100 mg, and L-Glutamine 25 mg per ml. The formulation targets GABAergic pathway modulation, circadian rhythm signaling, and neurotransmitter-associated metabolic mechanisms in preclinical research contexts. Each component has a defined neurological or metabolic research role: GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the mammalian central nervous system, acting on GABA-A (ionotropic, Cl⁻ channel) and GABA-B (metabotropic, K⁺/Ca²⁺) receptors; Melatonin is the pineal hormone that regulates circadian rhythm via MT1 and MT2 melatonin receptors, with additional antioxidant activity as a hydroxyl radical scavenger; L-Arginine is the substrate for neuronal nitric oxide synthase (nNOS) and is studied in neurological contexts for NO-mediated synaptic signaling; L-Glutamine is the primary brain ammonia buffer and an inter-organ nitrogen carrier, serving as a precursor for both glutamate and GABA synthesis. Peptides of China supplies Relaxation PM as a sterile liquid formulation with component concentrations verified by the manufacturer per batch. For laboratory research use only.

Profile

Components per ml GABA 100 mg, Melatonin 1 mg, L-Arginine 100 mg, L-Glutamine 25 mg

Research Areas

GABAergic neuropharmacology, circadian biology, neuronal NO signaling, sleep/wake cycle research, ammonia metabolism

Available Variants

Name Strength Pack Size Purity Availability
Relaxation PM 10 ml 10 vials >=98% In Stock

Specification Highlights

Quality & Testing

Testing method: HPLC / LC-MS . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control, using methods such as HPLC and LC-MS. These results are kept in the manufacturer’s internal quality-control records and are not issued as a separate certificate or document.

Research Areas

GABAergic Pathway Research GABA-A and GABA-B receptor pharmacology is studied in neuronal cell cultures (primary cortical neurons, GABAergic interneuron preparations) and brain slice preparations. GABA-A receptor modulation (chloride conductance, inhibitory postsynaptic potential frequency and amplitude) and GABA-B receptor signaling (Gi/o-coupled K⁺ channel activation, Ca²⁺ channel inhibition) are measured electrophysiologically. The Glutamine-Glutamate-GABA cycle — where Glutamine is converted by glutaminase to Glutamate and then by GAD (glutamic acid decarboxylase) to GABA — is an additional research axis provided by the L-Glutamine component. Circadian Rhythm and Melatonin Signaling Melatonin acts on MT1 receptors to suppress SCN (suprachiasmatic nucleus) firing and on MT2 receptors to phase-shift the circadian clock. Research using melatonin examines receptor binding kinetics (radioligand displacement with 2-[¹²⁵I]-iodomelatonin), circadian phase resetting (Per1/Per2 gene expression in circadian reporter cell lines), and antioxidant activity (ORAC, DPPH assays). Combined with GABA (which also modulates SCN activity via GABA-A receptors), the formulation provides dual inhibitory tone for sleep-related neurophysiology research.

Frequently Asked Questions

What are the research applications for Relaxation PM?

Primary research areas include: GABAergic neuropharmacology (GABA-A/B receptor studies in neuronal models), circadian rhythm biology (melatonin MT1/MT2 receptor pharmacology, circadian phase shifting), neuronal NO signaling (nNOS substrate with L-Arginine), and glutamine-GABA metabolic cycling. The combination is also used in sleep-wake cycle research examining the combined inhibitory effects of GABA and Melatonin on SCN activity.

Does systemic GABA cross the blood-brain barrier?

Endogenous GABA has limited CNS penetration via systemic administration under normal physiological conditions due to low BBB permeability. In vitro and ex vivo neurological research — using primary neuronal cultures, brain slice preparations, or direct CNS administration models — circumvents this limitation. For systemic research designs examining peripheral GABA receptor systems (enteric nervous system, immune cells), the compound is studied in those peripheral contexts directly.

What are the storage requirements?

Relaxation PM should be stored at 2-8°C, protected from light. Do not freeze. Use within the date specified on the label. For laboratory research use only. Not for human or veterinary use. Peptides of China is a B2B wholesale supplier operating under strict research-use-only terms. All products are sold exclusively for in vitro and preclinical research purposes. class, and every listing carries the manufacturer’s own specification rather than a reseller’s claim. Buyers sourcing chinese peptides in this category typically evaluate relaxation-pm across GABAergic neuropharmacology, circadian biology, neuronal NO signaling, sleep/wake cycle research, ammonia metabolism Form Sterile liquid formulation Storage 2-8°C; protect from light; do not freeze Sequence N/A — complex mixture CAS Number N/A — complex mixture Molecular Formula N/A — complex mixture Molecular Weight N/A — complex mixture

Research use only. This product is a research compound intended for laboratory research purposes. It is not for human or veterinary use, and is not a medicine, dietary supplement, or cosmetic.

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